Oligodendroglioma

Music to Ave Maria by F. Schubert, Lyrics by Arie Perry, MD

Oligodendroglioma, diffuse cerebral tumor of adults
Invading cortex, causing epilepsy; on imaging, often you are calcified
And although, you tend to progress over time, for long periods your fine

You're famous for your rounded nuclei, clear haloes look like honeycombs or fried eggs
With branching chicken wire capillaries, and perineuronal satellitosis


Oligodendroglioma, genetically, you are quite unique
With 1p and 19q deletions, from translocation with loss of one derivative
Represents a genetically favorable set, when FISH criteria are met

Anaplastic cases grow more rapidly, assigned a W.H.O. grade III
With microvascular proliferation, or increased mitotic activity
Oligodendroglioma